In a metaphysical thriller, 10 strangers get caught in a massive rainstorm while en route to different destinations and end up finding shelter at a remote desert motel. The gathering includes a limo driver (John Cusack), a cop (Ray Liotta), a prostitute (Amanda Peet), an aging TV actress (Rebecca DeMornay), bickering newlyweds (William Lee Scott and Clea DuVall), a prisoner (Jake Busey), and a family (John McGinley, Leila Kenzle and Bret Loehr). That night they live a nightmare as they are stalked by a killer who is murdering them one by one. They come to the frightening realization that their arrival at the hotel was no mere coincidence; they were drawn to the hotel by an evil, sadistic force. Most of them panic, but they must work together to find a way of escape from this unimaginable evil.